Determining the structures of new natural products from marine species not only enriches our understanding of the diverse chemistry of these species, but can also lead to the discovery of compounds with novel and/or important biological activities. Herein, we describe the isolation of isomaneonene C (), a new halogenated C acetogenin, and three known compounds, -snyderol (), -maneonene D (), and isomaneonene B (), from the organic extract obtained from the red alga cf. collected from Iheya Island, Okinawa, Japan. The structures of these secondary metabolites were elucidated spectroscopically. All compounds were inactive at 30 μg/disc against methicillin-resistant (MRSA) in combination treatment with a βlactam drug, meropenem.
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| http://dx.doi.org/10.1080/10286020.2022.2130266 | DOI Listing |
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