AI Article Synopsis
- - Quinoline and 1,3,4-oxadiazole are key heterocyclic compounds used in industrial and organic chemistry with a wide range of medical applications.
- - These compounds have been investigated for their potential in treating various health issues, including cancer, bacterial infections, and viral diseases, among others.
- - The review discusses the synthesis and biological activity of quinoline-1,3,4-oxadiazole hybrids, highlighting their structure-activity relationships from research primarily conducted between 2010 and 2021.
Article Abstract
Due to their diverse applications in industrial and synthetic organic chemistry, quinoline and 1,3,4-oxadiazole have become important heterocyclic compounds. Quinoline and 1,3,4- oxadiazole compounds have been developed for various medical conditions such as anti-cancer, anti-bacterial, anti-fungal, antimalarial, antioxidants, anti-HIV, anticonvulsant, antiviral, etc. The current review includes synthetic protocols for biologically active 1,3,4-oxadiazole incorporating quinoline hybrids with their structure-activity relationship to explore work (Mainly from 2010 to 2021) based on 1,3,4-oxadiazole-quinoline hybrids to the medicinal chemist for further research in the development of the molecule.
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| http://dx.doi.org/10.2174/1570179420666221004142659 | DOI Listing |
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