AI Article Synopsis
- Priapism, a rare yet urgent condition associated with Chronic Myeloid Leukaemia (CML), can lead to impotence if not treated promptly.
- Treatment options include medications like hydroxyurea and analgesics, along with surgical interventions and therapies like leukapheresis which effectively lowers leukocyte counts.
- In a reported case, multiple treatments were tried but failed to relieve pain until leukapheresis was administered, significantly reducing the priapism pain.
Article Abstract
Priapism is a rare presentation of Chronic Myeloid Leukaemia (CML). It is also considered a medical emergency as delay in treatment may lead to impotence. Prompt medical and surgical interventions such as hydroxyurea, analgesia, phenylephrine injection and aspiration, open surgical shunting, and local radiation therapy are essential. Leukapheresis effectively reduces leukocyte count rapidly and effectively, thereby an important therapy along with other standard of care in CML-induced priapism. In the present case, priapism was the presenting symptom of CML. The same was managed with various modalities such as hydroxyurea, allopurinol, antibiotics, analgesics, sedatives, phenylephrine injection, and aspiration but failed to reduce priapism pain. With a single cycle of leukapheresis, priapism pain could be reduced significantly.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9528545 | PMC |
| http://dx.doi.org/10.4103/ajts.ajts_160_21 | DOI Listing |
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