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Department of Biology, Indiana University, Bloomington, IN, USA.
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The relation between testosterone replacement therapy (TRT) and anterior cruciate ligament injury risk has garnered attention in recent orthopaedic research. With TRT's popularity on the rise, understanding its potential musculoskeletal risks is important for orthopaedic and sports medicine providers. Whereas some studies suggest an association, confounding variables such as activity level, number of hours of sports participation, dosing variations, physiological versus supraphysiological levels of testosterone, and individual patient characteristics may influence outcomes.
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Lower sex-hormone-binding globulin and faster maturation elevate free-testosterone-for-age in girls with obesity.
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Endocrinology Department, Hospital Sant Joan de Déu, University of Barcelona, 08950 Esplugues, Barcelona, Spain & CIBERDEM, Instituto de Salud Carlos III, 28029 Madrid, Spain.
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