AI Article Synopsis

  • * Of the 375 patients studied, those in the inpatient group had more health complications, lower blood counts, and higher rates of repeated bleeding and mortality compared to their outpatient counterparts.
  • * Key findings indicated that factors like endoscopic high-risk signs and existing health issues significantly increased the risk of rebleeding and death in hospitalized patients, highlighting the need for tailored care strategies for this group.

Article Abstract

Objective The study objectives were to clarify the clinical findings and the causes of intractability and mortality of upper gastrointestinal (UGI) bleeding in inpatients. Methods The patients were divided into Inpatient (Ip) and Outpatient (Op) onset groups, and their characteristics, clinical and bleeding data, and outcomes were compared. Patients Our study included 375 patients who developed UGI bleeding during hospitalization or were admitted after being diagnosed with UGI bleeding in an outpatient setting from January 1, 2015, to June 30, 2020. Results The Ip group had worse general condition; increased percentages of comorbidities; and more common use of proton pump inhibitor, anti-coagulant, and steroid than the Op group. Compared with the Op group, the Ip group had lower serum albumin levels and platelet counts at the onset of bleeding, whereas rebleeding, mortality, and bleeding-related death rates were higher. Multivariate analysis of the Ip group revealed that the risks of rebleeding included endoscopic high-risk stigmata, maintenance dialysis, and duodenal bleeding, whereas the risks of mortality were gastric ulcer and a Charlson Comorbidity Index update score of ≥3. Conclusion UGI bleeding in the Ip group was associated with higher rebleeding and mortality rates. Because of their poor general health condition, the pathology of UGI bleeding in these patients may differ from that of patients with common UGI bleeding. A different approach for the care and prevention of UGI bleeding in inpatients is required.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258105PMC
http://dx.doi.org/10.2169/internalmedicine.0614-22DOI Listing

Publication Analysis

Top Keywords

ugi bleeding
28
bleeding inpatients
12
bleeding
11
upper gastrointestinal
8
rebleeding mortality
8
ugi
7
group
6
patients
5
characteristics outcomes
4
outcomes risk
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!