A long-wavelength xanthene dye for photoacoustic imaging.

Chem Commun (Camb)

Department of Chemistry, University of California, Berkeley, CA, 94720, USA.

Published: October 2022

Photoacoustic (PA) imaging is a powerful biomedical imaging modality. We designed KeTMR and KeJuR, two xanthene-based dyes that were readily obtained through a 2-step synthetic route. KeJuR has low molecular weight, good aqueous solubility, and superior chemical stability compared to KeTMR. KeJuR shows a robust PA signal under 860 nm excitation and can be paired with traditional PA dyes for multiplex imaging in blood samples under a tissue-mimicking environment.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634815PMC
http://dx.doi.org/10.1039/d2cc03947hDOI Listing

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