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In vitro effect of hCG on cryptorchid patients' gubernacular cells: a predictive model for adjuvant personalized therapy.
Cell Commun Signal
January 2025
Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Background: Cryptorchidism is the absence of one or both testicles in the scrotum at birth, being a risk factor for testis cancer and infertility. The most effective method to treat cryptorchidism is orchiopexy, followed by human chorionic gonadotropin (hCG) therapy; however, a portion of treated patients do not show a significant improvement in testis volume and vascularization after adjuvant therapy.
Methods: In this study, we generated an in vitro model to predict the patient response to hCG by cultivating and treating primary cells derived from five cryptorchid patients' biopsies of gubernaculum testis, the ligament that connects the testicle to the scrotum.
Giant primary omental cyst: an unusual cause of pseudoascites and hydrocele in a child.
J Surg Case Rep
December 2024
Department of Pediatric Surgery, Hamad Medical Cooperation, Doha 2001, Qatar.
Abdominal lymphangiomas are benign congenital abnormal dilatation and proliferation of lymphatic spaces primarily seen in children. The wide spectrum of symptoms challenges preoperative diagnoses. We present a rare case of a 2-year-old boy presented to pediatrician with massive abdominal distention and left scrotal swelling since the age of 1½ years.
View Article and Find Full Text PDFMassive scrotal lymphedema in hidradenitis suppurativa: the surgical management of a severe case.
Int J Dermatol
November 2024
Department of Dermatology, Allergology and Venerology, International Centre for Acne Inversa/Hidradenitis Suppurativa (ICH), Ruhr-University Bochum, Bochum, Germany.
An Unexpected Giant: A Case of Massive Paratesticular Extra-mammary Myofibroblastoma.
Cureus
August 2024
General Surgery, Ayub Medical College, Abbottabad, PAK.
Mammary-type myofibroblastomas (MFBs) are benign spindle cell tumors, typically presenting in common locations such as the breast, abdomen, and inguinal region. We present a case of a 66-year-old male with a four-year history of painless scrotal swelling. The preoperative diagnosis was challenging, with an initial suspicion of soft tissue sarcoma.
View Article and Find Full Text PDFMassive scrotal elephantiasis: A case report.
Urol Case Rep
September 2024
Department of Urology B, CHU Ibn Sina, Faculty of Medicine and Pharmacy, Mohamed V University, Rabat, Morocco.
The condition known as scrotal elephantiasis is a debilitating rarity where the scrotum undergoes significant swelling, typically arising from chronic obstructive lymphedema. A case is presented of a 60-year-old man who had suffered severe and persistent enlargement of his scrotum for multiple years. This affliction greatly affected both his ability to function effectively and caused detrimental psychosocial consequences.
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