Avirulence: an essential feature of the parasitic lifestyle.

Trends Parasitol

Center for Immunity and Inflammation, Department of Medicine, New Jersey Medical School, Rutgers University, Newark, NJ, USA. Electronic address:

Published: December 2022

AI Article Synopsis

  • The host is crucial in how parasites are transmitted and can influence the success of this relationship.
  • The effectiveness of the host and parasite interaction relies on the host's ability to develop immune resistance and tolerate potential diseases.
  • The idea presented is that parasites evolve to possess factors that help their hosts tolerate diseases, which is a key aspect of their life cycle.

Article Abstract

The host plays an essential role in parasite transmission. The viability of the host-parasite relationship depends upon development of immune resistance and the induction of disease tolerance. Here I propose that pathogen coevolution of avirulence factors promoting host disease tolerance is an essential feature of the parasitic lifestyle.

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Source
http://dx.doi.org/10.1016/j.pt.2022.09.003DOI Listing

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