Purpose Of Review: Stress plays a central role in the onset and course of depression. However, only a subset of people who encounter stressful life events go on to experience a depressive episode. The current review highlights recent advances in understanding when, why, and for whom the stress-depression link occurs, and we identify avenues for future research.
Recent Findings: In the last 18 months, researchers have taken a more nuanced perspective on the biopsychosocial mechanisms critical to the stress-depression link. For example, examination of specific facets of emotion regulation, including emotion regulation flexibility and interpersonal emotion regulation, has been critical to understanding its role in depression. Similarly, refined investigations of social support allowed researchers to identify distinct - and occasionally opposite - outcomes depending on the context or manner in which the support was provided. Researchers also documented that the stress-depression link was enhanced by dysregulation of several stress-sensitive biological systems, such as the immune system, microbiome, endocrine system, and neuroanatomical substrates.
Summary: Recent studies highlight the importance of adopting a nuanced understanding of mechanisms and moderators that explain the stress-depression link. We also encourage continued engagement in collaborative, open science that uses multiple methods to study the full breadth of human diversity.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/YCO.0000000000000831 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The effectiveness of multimedia mental health self-care program based on cyber space on the mental health of infertile women: a randomized controlled trial.
BMC Psychol
November 2024
Department of Basic Sciences, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: So far, some training interventions have been carried out to improve the mental health in women with infertility, but designing the need and evidence-based, as well as multimedia mental health self-care interventions based on cyber space has received less attention. Due to the spread of the internet and the role of self-care in improving mental disorders, this study was conducted to evaluate the effectiveness of the multimedia mental health self-care program on mental health and to assess the users' satisfaction.
Methods: This study is a randomized controlled trial with pretest-posttest follow-up design.
Nursing in the digital age: The role of nursing in addressing cyberbullying and adolescents mental health.
J Psychiatr Ment Health Nurs
February 2025
Psychiatric and Mental Health Nursing, Faculty of Nursing, Alexandria University, Alexandria, Egypt.
The Relevance Of Our Study To Mental Health Nursing: What is known on the subject? The study's findings are crucial for mental health nursing, as they highlight the significant impact of cyberbullying on adolescents' mental health in Egypt. What this paper adds to existing knowledge? By establishing a clear link between cyberbullying, family income, and mental health issues such as anxiety, stress, and depression, the research underscores the need for targeted interventions and support systems. What are the implications for practice? Mental health nurses can utilize this information to develop effective prevention and treatment strategies, advocate for policy changes, and educate families and communities.
View Article and Find Full Text PDFDirect and Indirect Effects of Stress and Self-Esteem on Primary Dysmenorrhea in Korean Adolescent Girls: A Cross-Sectional Survey Study.
Iran J Public Health
January 2024
Graduate School of Alternative Medicine, Kyonggi University (Seoul Campus), Seoul, Republic of Korea.
Article Synopsis
- The study explores the impact of stress and self-esteem on primary dysmenorrhea (menstrual pain) in adolescent girls aged 15-18 in South Korea.
- Stress, depression, and anxiety were found to increase menstrual pain, while higher self-esteem was linked to lower levels of negative emotions and dysmenorrhea.
- The results suggest that managing mental health factors like stress and self-esteem is crucial for alleviating menstrual pain in adolescents.
Lonely and scrolling during the COVID-19 pandemic: understanding the problematic social media use and mental health link among university students.
Front Psychiatry
January 2024
Department of Neuroscience, Carleton University, Ottawa, ON, Canada.
Introduction: Undergraduate university students experienced many academic and non-academic stressors during the first year of the coronavirus (COVID-19) pandemic, putting them at a greater risk of negative mental health outcomes. Reports worldwide have shown high incidences of depressive, anxiety, and stress scores among university students at the beginning of the pandemic. Emerging evidence also suggests that to cope with the stress and loneliness of the pandemic, many youth and young adults increased the amount of time they spent on social media platforms.
View Article and Find Full Text PDFChronic Stress, Depression, and Alzheimer's Disease: The Triangle of Oblivion.
Adv Exp Med Biol
October 2023
Institute of Biosciences and Applications, NCSR Demokritos, Athens, Greece.
Chronic stress and high levels of the main stress hormones, and glucocorticoids (GC), are implicated in susceptibility to brain pathologies such as depression and Alzheimer's disease (AD), as they promote neural plasticity damage and glial reactivity, which can lead to dendritic/synaptic loss, reduced neurogenesis, mood deficits, and impaired cognition. Moreover, depression is implicated in the development of AD with chronic stress being a potential link between both disorders via common neurobiological underpinnings. Hereby, we summarize and discuss the clinical and preclinical evidence related to the detrimental effect of chronic stress as a precipitator of AD through the activation of pathological mechanisms leading to the accumulation of amyloid β (Aβ) and Tau protein.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!