We present our experience in using artificial skin (Omniderm) in the prevention of early healing of a raw lid margin. The material is inert and acts properly for this procedure.
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A stretchable, adhesive, and wearable hydrogel-based patches based on a bilayer PVA composite for online monitoring of sweat by artificial intelligence-assisted smartphones.
Talanta
January 2025
Department of Materials Science and Engineering, Sharif University of Technology, Azadi Avenue, Tehran, 14588-89694, Iran; Center for Bioscience and Technology, Institute for Convergence Science and Technology, Sharif University of Technology, Tehran, 14588-89694, Iran; Fraunhofer Institute for Manufacturing Technology and Advanced Materials, 28359, Bremen, Germany. Electronic address:
Real-time monitoring of sweat using wearable devices faces challenges such as limited adhesion, mechanical flexibility, and accurate detection. In this work, we present a stretchable, adhesive, bilayer hydrogel-based patch designed for continuous monitoring of sweat pH and glucose levels using AI-assisted smartphones. The patch is composed of a bottom PVA hydrogel layer functionalized with colorimetric reagents and glucose oxidase enzyme, while the top PVA-sucrose layer enhances skin adhesion and protects against air moisture.
View Article and Find Full Text PDFPrebiotics Beyond the Gut: Omics Insights, Artificial Intelligence, and Clinical Trials in Organ-Specific Applications.
Probiotics Antimicrob Proteins
January 2025
Faculty of Pharmacy and Medical Sciences, University of Petra, Amman, 11196, Jordan.
Prebiotics, traditionally linked to gut health, are increasingly recognized for their systemic benefits, influencing multiple organ systems through interactions with the gut microbiota. Compounds like inulin, fructooligosaccharides (FOS), and galactooligosaccharides (GOS) enhance short-chain fatty acid (SCFA) production, benefiting neurocognitive health, cardiovascular function, immune modulation, and skin integrity. Advances in biotechnology, including deep eutectic solvents (DES) for extraction and machine learning (ML) for personalized formulations, have expanded prebiotic applications.
View Article and Find Full Text PDFEnhanced virulence of Acinetobacter johnsonii at low temperatures induces acute immune response and systemic infection in American bullfrogs (Aquarana catesbeiana).
Vet Microbiol
January 2025
Guangzhou Key Laboratory of Aquatic Animal Diseases and Waterfowl Breeding, Innovative Institute of Animal Healthy Breeding, College of Animal Sciences and Technology, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China. Electronic address:
Acinetobacter johnsonii is a denitrifying bacterium commonly used as an environmental probiotic in wastewater treatment. However, research on its potential pathogenicity to animals is limited. During an epidemiological survey conducted from 2022 to 2024 at bullfrog farms in Guangdong Province, China, multiple strains were isolated from diseased bullfrogs during the low-temperature season.
View Article and Find Full Text PDFUser and Developer Views on Using AI Technologies to Facilitate the Early Detection of Skin Cancers in Primary Care Settings: Qualitative Semistructured Interview Study.
JMIR Cancer
January 2025
Wolfson Institute of Population Health, Queen Mary University of London, London, United Kingdom.
Background: Skin cancers, including melanoma and keratinocyte cancers, are among the most common cancers worldwide, and their incidence is rising in most populations. Earlier detection of skin cancer leads to better outcomes for patients. Artificial intelligence (AI) technologies have been applied to skin cancer diagnosis, but many technologies lack clinical evidence and/or the appropriate regulatory approvals.
View Article and Find Full Text PDFA Biomimetic Passive Mechanotransduction Mechanism Based on Interfacial Regulation of Ionic p-n Junctions.
ACS Nano
January 2025
School of Mechanical Engineering, Sichuan University, Chengdu 610065, China.
Natural skin receptors use ions as signal carriers, while most of the developed artificial tactile sensors utilize electrons as information carriers. To imitate the biological ionic sensing behavior, here, we present a kind of biomimetic, ionic, and fully passive mechanotransduction mechanism leveraging mechanical modulation of interfacial ionic p-n junction (IPNJ) through microchannels. Sensors based on this mechanism do not rely on an external power supply and can encode external tactile stimuli into highly analogous signal outputs to those of natural skin receptors, in terms of both signal type (i.
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