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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746757 | PMC |
| http://dx.doi.org/10.1097/CM9.0000000000002243 | DOI Listing |
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Article Synopsis
- The study compared the effectiveness and safety of remimazolam besylate to ciprofol in elderly patients during painless gastrointestinal endoscopy.
- Patients were divided into a control group (ciprofol) and an observation group (remimazolam besylate) to analyze various factors like anesthesia onset time, recovery time, hemodynamics, and cognitive function.
- Results indicated that remimazolam besylate provided quicker anesthesia and recovery, more effective analgesia, better hemodynamic stability, and less cognitive impairment, with no significant difference in adverse reactions between the two groups.
- Overall, remimazolam besylate was found to be a superior choice for elderly patients in this procedure.
Effect of remimazolam besylate versus propofol on haemodynamic profiles in patients undergoing thyroid surgery with recurrent laryngeal nerve monitoring: a protocol for a randomised controlled trial.
BMJ Open
November 2024
Department of Anaesthesiology, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, Guangdong, China
Article Synopsis
- Thyroid surgery requiring nerve monitoring often needs deeper sedation, which can cause blood pressure instability.
- A study is comparing remimazolam, a new sedative, with propofol to see which better supports stable hemodynamics during surgery.
- The trial will randomly assign 284 patients to either sedative, focusing on outcomes like hypotension and the overall safety of each sedative combination.
Comparison of the anesthetic effects of remimazolam tosilate and remimazolam besylate in daytime hysteroscopic surgery.
BMC Anesthesiol
October 2024
Department of Anesthesiology, Weifang People's Hospital, No. 151 Guangwen Street, Kuiwen District, Weifang, 261041, China.
Article Synopsis
- The study aimed to compare the anesthetic effects of two forms of remimazolam (tositlate and besylate) in patients undergoing daytime hysteroscopic surgery.
- Fifty patients were randomly divided into two groups to evaluate differences in induction doses and various anesthesia-related outcomes.
- Results showed no significant differences between the two groups in terms of anesthesia induction, recovery time, and adverse effects, indicating both forms have similar anesthetic effects.
Severe Anaphylaxis From Remimazolam in a Mastocytosis Cancer Patient: A Case Report.
Cureus
September 2024
Department of Anesthesiology and Perioperative Medicine, MD Anderson Cancer Center, Houston, USA.
Remimazolam besylate is a novel, rapid-onset, ultra-short-acting benzodiazepine with an advantageous cardio-respiratory safety profile. To date, there have been few published reports of remimazolam-induced anaphylaxis, none of which are documented in patients with mast cell disease. We describe the case of a 77-year-old male with oncologic mastocytosis who developed anaphylaxis following remimazolam administration.
View Article and Find Full Text PDFUnveiling the impact of airways: A comparative analysis of oropharyngeal and nasopharyngeal airways in painless fiberoptic bronchoscopy.
Heliyon
August 2024
Department of Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Article Synopsis
- This study compared the effectiveness of oropharyngeal airways (OA) and nasopharyngeal airways (NA) in keeping patients oxygenated during painless fiberoptic bronchoscopy while under sedation with remimazolam besylate.
- Out of 252 patients, those using NA experienced more hypoxemia and had lower oxygen saturation levels during the procedure compared to those using OA.
- The findings suggest that OA might be safer for maintaining respiratory function during the procedure, especially for patients with higher body mass index (BMI).
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