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Short-term Postoperative Complications of Lymphatic Malformation Surgical Excision: A 20-Year Institutional Review.
J Pediatr Surg
January 2025
Division of Pediatric Surgery, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Objective: To evaluate outcomes and postoperative complications following surgical resection of lymphatic malformations (LMs) at a single multidisciplinary vascular anomalies center.
Methods: A single-center retrospective review of all patients ≤21 years old who underwent surgical resection of a lymphatic malformation at a quaternary referral center with a multidisciplinary vascular anomalies team from 2004 to 2024. Data pertaining to postoperative outcomes and treatments was abstracted.
Impaired Wnt/Planar Cell Polarity Signaling in Yellow Nail Syndrome.
Ann Intern Med
January 2025
The Genetics Institute and Genomics Center, Tel Aviv Sourasky Medical Center, and School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel (H.B.F.).
Article Synopsis
- Yellow Nail Syndrome (YNS) is a rare condition marked by yellow, malformed nails, swelling due to lymphedema, and chronic lung issues, typically presenting in adulthood, with potential genetic links suggested.
- Researchers conducted genetic sequencing and expression studies on 11 patients (6 with congenital YNS and 5 with sporadic YNS) to investigate its underlying causes.
- Findings revealed biallelic variants in genes related to the Wnt/planar cell polarity pathway in congenital cases, indicating that defects in cellular organization could be key to understanding YNS's development, though the study's small sample size is a limitation.
Monitoring lymphatic reconstitution in free latissimus dorsi flap for lower extremity defects repair in pediatric patients: a case series.
Transl Pediatr
November 2024
Department of Burns and Plastic Surgery, Children's Hospital of Nanjing Medical University, Nanjing, China.
Background: The circulation in free flap is mainly studied on blood perfusion, but lack of exploring contributory factor of lymphatic drainage. This study aimed to monitor lymphatic reconstitution of free latissimus dorsi (LD) flaps for lower extremity defects repair, using indocyanine green (ICG) lymphography and assessing its relationship with post-operative flap edema.
Methods: Patients who underwent lower extremity defects repair with free LD flap between January 2021 and April 2024 were included.
A Very Rare Side Effect of Sirolimus in a Child with Autoimmune Hemolytic Anemia: Lymphedema.
Turk Arch Pediatr
November 2024
Department of Pediatric Hematology and Oncology, Ankara Yıldırım Beyazıt University, Ankara City Hospital, Ankara, Türkiye.
Anaphylaxis to cow's milk protein in a probiotic not detected by the electronic medical record.
JPGN Rep
November 2024
Allergy Partners of NJ Ocean New Jersey USA.
A 13-year-old female with a history of congenital left lower leg lymphedema, multiple food allergies, including an immunoglobulin E mediated severe cow's milk allergy, and well-controlled moderate persistent asthma was hospitalized with left lower leg erysipelas and Group A Streptococcus septicemia. While hospitalized, immediately after exposure to cow's milk protein as an inactive ingredient within a probiotic, she developed anaphylaxis with respiratory failure requiring intubation. This is only the third reported case of anaphylaxis due to a probiotic.
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