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| http://dx.doi.org/10.1002/aet2.10811 | DOI Listing |
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Bedside implications of the use of surrogate endpoints in solid and haematological cancers: implications for our reliance on PFS, DFS, ORR, MRD and more.
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Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA.
Clinical endpoints, such as overall survival, directly measure relevant outcomes. Surrogate endpoints, in contrast, are intermediate, stand-in measures of various tumour-related metrics and include tumour growth, tumour shrinkage, blood results, etc. Surrogates may be a time point measurement, that is, tumour shrinkage at some point (eg, response rate) or biomarker-assessed disease status, measured at given time points (eg, circulating tumour DNA, ctDNA).
View Article and Find Full Text PDFFrom books to the bedside: post-graduation impact of 'Week On the Wards' on medical education.
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Cooper Medical School of Rowan University, 401 Broadway, Camden, New Jersey, 08103, USA.
Background: The transition between preclinical and clinical years during medical school has been shown to be challenging. Cooper Medical School of Rowan University (CMSRU) implements one required two-week-long shadowing program for first and one one-week-long shadowing program for second-year medical students called Week On the Wards (WOW). The goal of this study is to ascertain whether students who completed the WOW curriculum found it beneficial over the long-term.
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Department of Geriatric Medicine, Odense University Hospital, Odense, Denmark.
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View Article and Find Full Text PDFExtended use of point-of-care technology versus usual care for in-home assessment by acute community nurses in older adults with signs of potential acute respiratory disease: an open-label randomised controlled trial protocol.
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Department of Geriatric Medicine, Geriatric Research Unit, Odense University Hospital, Odense, Denmark.
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View Article and Find Full Text PDFGiving Literal Thanks: An ACGME-Sponsored Initiative to Bring Residents Back to the Bedside.
J Grad Med Educ
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is Assistant Professor, Department of Pediatrics, MassGeneral for Children and Harvard Medical School, Boston, Massachusetts, USA.
Resident burnout is at an all-time high. In response, the Accreditation Council for Graduate Medical Education (ACGME) developed the Back to Bedside grant for resident-led burnout interventions that increase the time residents spend with patients. We designed a resident-patient reading intervention, Giving Literal Thanks (GLT), intended to increase meaningful time residents spend with patients and thereby decrease burnout.
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