Cryptolaevilactones (CLs) A-L, found in the leaves and twigs of Cryptocarya laevigata, are unique natural meroterpenoids with a spiro[3.5]nonane skeleton. We report the total synthesis of a simplified model compound of CLs A-C. The synthetic route included introduction of a styryl group and coupling of a lactone moiety to a spiro ring system, which was constructed by a pinacol-like rearrangement.
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