Cardiovascular disease (CVD) is the most fatal disease in the world, so its accurate and automated detection in the early stages will certainly support the medical expert in timely diagnosis and treatment, which can save many lives. Many types of research have been carried out in this regard, but due to the problem of data imbalance in the medical and health care sector, it may not provide the desired results in all aspects. To overcome this problem, a sequential ensemble technique has been proposed that detects 6 types of cardiac arrhythmias on large ECG imbalanced datasets, and the data imbalanced issue of the ECG dataset has been addressed by using a hybrid data resampling technique called "Synthetically Minority Oversampling Technique and Tomek Link (SMOTE + Tomek)". The sequential ensemble technique employs two distinct deep learning models: Convolutional Neural Network (CNN) and a hybrid model, CNN with Long Short-Term Memory Network (CNN-LSTM). The two standard datasets "MIT-BIH arrhythmias database" (MITDB) and "PTB diagnostic database" (PTBDB) are combined and extracted 23, 998 ECG beats for the model validation. In this work, the three models CNN, CNN-LSTM, and ensemble approach were tested on four kinds of ECG datasets: the original data (imbalanced), the data sampled using a random oversampled technique, data sampled using SMOTE, and the dataset resampled using SMOTE + Tomek algorithm. The overall highest accuracy was obtained of 99.02% on the SMOTE + Tomek sampled dataset by ensemble technique and the minority class accuracy result (Recall) is improved by 20% as compared to the imbalanced data.
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http://dx.doi.org/10.1016/j.compbiomed.2022.106142 | DOI Listing |
Biom J
April 2025
Department of Statistical Sciences, Università Cattolica del Sacro Cuore, Milan, Italy.
Supervised learning in presence of multiple sets of noisy labels is a challenging task that is receiving increasing interest in the ever-evolving landscape of healthcare analytics. Such an issue arises when multiple annotators are tasked to manually label the same training samples, potentially giving rise to discrepancies in class assignments among the supplied labels with respect to the ground truth. Commonly, the labeling process is entrusted to a small group of domain experts, and different level of experience and subjectivity may result in noisy training labels.
View Article and Find Full Text PDFTher Clin Risk Manag
March 2025
Department of Neurosurgery, The second Affiliated Hospital, Jiangxi Medical College of Nanchang University, Nanchang, 330006, People's Republic of China.
Background: Endovascular treatment (EVT) has been recommended as a superior modality for the treatment of intracranial aneurysm. However, there still exists a worse percentage of poor functional outcome in patients with poor-grade aneurysmal subarachnoid hemorrhage (aSAH) undergoing EVT. Therefore, it is urgently needed to investigate the risk factors and develop a critical decision model in the subtype of such patients.
View Article and Find Full Text PDFBiophys Rep
February 2025
Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China, Chengdu 611731, China.
Some microbes are referred to as model organisms because they are easy to study in the laboratory and hold the ability to retain their characteristics during DNA replication, DNA transcription, and other fundamental processes. Studying these microbes in living cells via single-molecule imaging allows us to better understand these processes at highly improved spatiotemporal resolution. Single particle tracking photoactivated localization microscopy (sptPALM) is a robust tool for detecting the positions and motions of individual molecules with tens of nanometers of spatial and millisecond temporal resolution , providing insights into intricate intracellular environments that traditional ensemble methods cannot.
View Article and Find Full Text PDFSci Rep
March 2025
Department of Petroleum and Geo-energy Engineering, Amirkabir University of Technology (Tehran Polytechnic), Tehran, Iran.
Given the application of cycloalkanes in surrogate blends for aviation fuels, their determination of critical characteristics pertinent to fuel transportation and combustion becomes imperative. In this study, we aim to construct intelligent models based on machine learning methods of random forest (RF), adaptive boosting, decision tree (DT), ensemble learning, K-nearest neighbors (KNN), support vector machine (SVM), multi-layer perceptron (MLP) artificial neural network and convolutional neural network (CNN) to predict the density of binary blends of ethylcyclohexane or methylcyclohexane with n-hexadecane/n-dodecane/n-tetradecane in terms of operational conditions (pressure and temperature) and cycloalkane mole fractions in n-alkanes, utilizing laboratory data extracted from existing scholarly publications. The reliability of the data used is affirmed using an outlier detection algorithm, and the relevancy factor concept is utilized to find the relative effects of the input parameters on the output parameter.
View Article and Find Full Text PDFSci Rep
March 2025
Faculty of Electrical and Computer Engineering, National Technical University of Athens, Athens, 15773, Greece.
An interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' interpretations. The dataset used comprises volumetric measurements from brain MRI and genetic data from healthy individuals and patients with MCI/AD, obtained through the Alzheimer's Disease Neuroimaging Initiative. The existing class imbalance is addressed by an ensemble learning approach, while various attribution-based and counterfactual-based interpretability methods are leveraged towards producing diverse explanations related to the pathophysiology of MCI/AD.
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