Numerous studies have confirmed the importance of recent "life events" in triggering a psychiatric episode, whereas the so-called predisposing effect of past events is less well known. The present study analyzes the results of a retrospective documentation of the AMDP anamnestic forms in hospitalized patients. In order to avoid the influence of the evolution of psychopathology in itself, only first episode patients were included. The sociodemographic data and the life events were analyzed separately for three diagnostic groups: schizophrenias, neurotic/reactive depressions, nondepressed neurotics. The most significant result was the loss of a parent before 15 years of age in the group of depressed patients; this difference was confirmed by matching the groups for age sex, marital status and profession.
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Front Plant Sci
January 2025
Institut Sénégalais de Recherches Agricoles (ISRA/Centre d'Etude Regional pour l'Amélioration de l'Adaptation à la Sécheresse (CERAAS), Thies, Senegal.
Early leaf spot (ELS), caused by (syn. ), is a highly damaging peanut disease worldwide. While there are limited sources of resistance in cultivated peanut cultivars, wild relatives carry alleles for strong resistance, making them a valuable strategic resource for peanut improvement.
View Article and Find Full Text PDFiScience
January 2025
Microbiology and Immunology Department, School of Medicine, Faculty of Medical Science, Jinan University, Guangzhou 510632, Guangdong, China.
γδ T cells play protective roles in tuberculosis (TB). Our work demonstrated the therapeutic potential of allogeneic Vγ9Vδ2 T cells in TB patients. However, their functions in TB require further comprehensive evaluation.
View Article and Find Full Text PDFJ Oral Biol Craniofac Res
January 2025
Department of Periodontics, Vivekanandha Dental College for Women, India.
Background And Objective: Periodontitis and dental caries are among the most prevalent oral diseases, with chronic periodontitis being a multifactorial, infectious condition that leads to inflammation in the supporting structures of the teeth, progressive attachment loss, and bone resorption. Chronic periodontitis is driven by a consortium of pathogenic microorganisms. This study aimed to evaluate the efficacy of virgin coconut oil (VCO) pulling in reducing the microbial load and inflammatory mediators responsible for chronic periodontitis, in comparison to chlorhexidine (CHX) mouthwash and distilled water.
View Article and Find Full Text PDFDrug Des Devel Ther
January 2025
Department of Pharmaceutical Sciences and Pharmaceutics, Faculty of Pharmacy, Applied Science Private University, Amman, 11937, Jordan.
Introduction: The beneficial effects of probiotics are encountered by their low viability in gastrointestinal conditions and their insufficient stability during manufacturing, throughut the gastrointestinal transit, and storage. Therefore, novel systems are highly required to improve probiotics delivery.
Methods: In this study, Lactobacillus gasseri (L), Bifidobacterium bifidum (B), and a combination of L+B were encapsulated in chitosan (CS)-polyacrylic acid (PAA) complex systems (CS-PAA).
J Glob Infect Dis
December 2024
Leônidas and Maria Deane Institute, Oswaldo Cruz Foundation, Manaus, Amazonas State, Brazil.
Introduction: The tools to distinguish relapse from reinfection are needed in malaria-endemic areas. We evaluated seroprevalence against sets of specific peptides to the block 2 region of -merozoite surface protein-1 (PvMSP1) to detect parasite clones.
Methods: We applied amplicon deep sequencing (ADS) of block 2 region of the MSP-1 gene () to determine cocirculating parasite clones within eight -infected individuals.
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