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First characterization of the faecal resistome of eurasian otter (Lutra lutra), a sentinel species for aquatic environments. | LitMetric

First characterization of the faecal resistome of eurasian otter (Lutra lutra), a sentinel species for aquatic environments.

Chemosphere

CESAM and Department of Biology, University of Aveiro, Campus de Santiago, 3810-193, Aveiro, Portugal. Electronic address:

Published: December 2022

AI Article Synopsis

Article Abstract

Antimicrobial resistance (AMR) is a global health concern. Nowadays, antibiotic resistance genes (ARGs) are considered emerging pollutants. This study followed the One Health framework, in which AMR surveillance in the environment, including in wild animals, is advisable to mitigate this problem. Here we investigated AMR associated with Eurasian otter, a semi-aquatic mammal considered an indicator of freshwater health. To do so, otter's faecal resistome was characterized by a high-throughput qPCR array. This technique has a high-capacity of ARGs profiling. Additionally, we have assessed the antimicrobial susceptibility of two indicator bacteria, E. coli and Enterococcus spp, isolated from otter spraints and interpreted the results according to clinical and epidemiological cut-offs (ECOFFs).

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Source
http://dx.doi.org/10.1016/j.chemosphere.2022.136644DOI Listing

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