The interventional cytopathologist can successfully refine the differential diagnosis of a neck mass by combining ultrasonographical and morphological skills as shown in this case of head and neck paraganglioma, which was suspected thanks to ultrasound features and rapid‐on site evaluation and further confirmed by immunocytochemistry on cell block and by the subsequent histologic evaluation.
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http://dx.doi.org/10.1111/cyt.13185 | DOI Listing |
Acta Otolaryngol
January 2025
Otolaryngology Division, Azienda Ospedaliero Universitaria Sassari, Sassari, Italy.
Background: US guided sampling is a validated diagnostic approach for non-thyroid deep head and neck masses.
Aim: To describe the setting of a clinician-driven Lump Clinic and analyze a monoinstitutional 7-year database of 849 patients undergoing US-guided sampling.
Methods: FNA with Rapid OnSite Evalutation (ROSE) was the first diagnostic step.
NPJ Syst Biol Appl
January 2025
Department of Bioscience & Bioengineering, Indian Institute of Technology, Jodhpur, Rajasthan, India.
Classification of adenocarcinoma (AC) and squamous cell carcinoma (SCC) poses significant challenges for cytopathologists, often necessitating clinical tests and biopsies that delay treatment initiation. To address this, we developed a machine learning-based approach utilizing resected lung-tissue microbiome of AC and SCC patients for subtype classification. Differentially enriched taxa were identified using LEfSe, revealing ten potential microbial markers.
View Article and Find Full Text PDFBMC Cancer
January 2025
Department of Pathology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, China.
Objective: Rapid on-site evaluation (ROSE) of respiratory cytology specimens is a critical technique for accurate and timely diagnosis of lung cancer. However, in China, limited familiarity with the Diff-Quik staining method and a shortage of trained cytopathologists hamper utilization of ROSE. Therefore, developing an improved deep learning model to assist clinicians in promptly and accurately evaluating Diff-Quik stained cytology samples during ROSE has important clinical value.
View Article and Find Full Text PDFPathologica
December 2024
Department of Public Health, University of Naples Federico II, Naples, Italy.
Background: Although the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) has improved the diagnosis and management of salivary gland lesions, determining the risk of malignancy (ROM) for AUS and SUMP categories remains challenging. We investigated the role of interventional cytopathologists in refining the differential diagnosis of these categories.
Methods: We searched for salivary gland fine-needle aspirations (FNAs) performed at our Institution since the publication of the first edition of MSRSGC.
J Am Soc Cytopathol
December 2024
Department of Pathology and Cell Biology, Columbia University Medical Center, New York Presbyterian Hospital, New York, New York.
Introduction: The role of endoscopic ultrasound-guided fine-needle aspiration and fine-needle biopsy (EUS-FNA/B) in the clinical management of gastrointestinal lymphoma has not been extensively studied. This study investigates the use of EUS-FNA/B in the diagnosis of first-time and recurrent gastrointestinal lymphomas at a large academic institution.
Materials And Methods: A total of 40 patients who had final diagnosis of lymphoma according to the World Health Organization (WHO) classification of tumors of hematopoietic lymphoid tissues who underwent EUS-FNA/B were included in the study.
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