Neurologic and psychopathologic disturbances were studied in patients with DL-ephedrine addiction. The patients were also subjected to echoencephalography. The authors identified the period of acute narcotic intoxication, the abstinence syndrome and the period of chronic intoxication. The recommendations on the treatment of the above patients are presented.
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Addiction
June 2024
United Nations Office on Drugs and Crime, Research and Trends Analysis Branch, Vienna, Austria.
Background And Aims: The use and manufacture of methamphetamine has increased in Afghanistan in recent years. Recent research and reports have pointed to the ephedra plant, which grows wildly, as a key source of ephedrine used in the manufacture of methamphetamine. This paper aimed to estimate the relative efficiencies and scale of inputs required to manufacture methamphetamine in Afghanistan.
View Article and Find Full Text PDFJ Psychoactive Drugs
February 2024
School of Medicine, Western Michigan University, Kalamazoo, MI, United States.
The standard protocol in addiction treatment/pain management is to conduct immunoassay screens for major drugs subject to misuse, followed by confirmatory testing of positive results. However, this may miss unscreened or rarely screened drugs that could pose risks, especially to polydrug users. We sought to determine the prevalences of unscreened/rarely screened drugs in a sample of individuals misusing drugs in 7 U.
View Article and Find Full Text PDFInt Immunopharmacol
June 2022
NHC Key Laboratory of Drug Addiction Medicine, Kunming Medical University, Kunming 650032, China; School of Medicine, Yunnan University, Kunming 650500, China. Electronic address:
Drug withdrawal elicits immune responses that contribute to the development of withdrawal symptoms and relapse. The understanding of the immunologic dynamics after drug withdrawal is limited, precluding the finding of promising immune intervention measures. Here, we performed cytokine and multiplex immune profiling in heroin, methamphetamine (METH) and ephedrine users after withdrawal and identified the correlation between cytokines and other immune parameters.
View Article and Find Full Text PDFCNS Spectr
January 2022
Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia.
Background: Clozapine is the most effective medication for treatment-refractory schizophrenia but is associated with significant adverse drug reactions, including nocturnal enuresis and urinary incontinence. This side effect can be burdensome and lead to medication nonadherence and psychotic relapse. Evidence to guide treatment of clozapine-induced nocturnal enuresis and urinary incontinence is sparse.
View Article and Find Full Text PDFCochrane Database Syst Rev
October 2021
Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Background: Most people who stop smoking gain weight. This can discourage some people from making a quit attempt and risks offsetting some, but not all, of the health advantages of quitting. Interventions to prevent weight gain could improve health outcomes, but there is a concern that they may undermine quitting.
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