We prepare high-filling two-component arrays of tens of fermionic ^{6}Li atoms in optical tweezers, with the atoms in the ground motional state of each tweezer. Using a stroboscopic technique, we configure the arrays in various two-dimensional geometries with negligible Floquet heating. A full spin- and density-resolved readout of individual sites allows us to postselect near-zero entropy initial states for fermionic quantum simulation. We prepare a correlated state in a two-by-two tunnel-coupled Hubbard plaquette, demonstrating all the building blocks for realizing a programmable fermionic quantum simulator.
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