Identification of specific alterations in tumors (as a rule, these are mutations or gene fusions) makes it possible to prescribe targeted drugs of the second line of therapy or, in some cases of inoperable tumors, to observe not only a gradual partial response of the tumor to treatment, but also the removal of these patients from the category of incurable ones. The article describes a new rare type of gene fusion detected in a piloid astrocytoma that developed in the posterior cranial fossa in an 11-year-old boy.

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http://dx.doi.org/10.17116/patol20228405140DOI Listing

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