We report a 24-year-old female patient not infected with human immunodeficiency virus (HIV) and without other risk factors of immunosuppression, presenting with neuromeningeal cryptococcosis. Cerebrospinal fluid (CSF) analysis revealed the presence of . The evolution was unfavorable and the patient died even after appropriate antifungal treatment.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474906PMC
http://dx.doi.org/10.1002/ccr3.6353DOI Listing

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Neuromeningeal cryptococcosis is a life-threatening infection of the central nervous system, caused by encapsulated yeast belonging to the and species complexes. Recent data showed that virulence and antifungal resistance are variable for yeasts belonging to the species complex. There is an increase in resistance to fluconazole for yeasts of the species complex and the virulence is variable according to the genotype.

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April 2023

Biology Department, Medical Analysis Laboratory, Mohammed VI University Hospital of Marrakech, Faculty of Medicine and Pharmacy of Marrakech, Cadi Ayyad University, Marrakech, MAR.

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We report a 24-year-old female patient not infected with human immunodeficiency virus (HIV) and without other risk factors of immunosuppression, presenting with neuromeningeal cryptococcosis. Cerebrospinal fluid (CSF) analysis revealed the presence of . The evolution was unfavorable and the patient died even after appropriate antifungal treatment.

View Article and Find Full Text PDF

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