Recent studies in neuroeducation highlight the benefits of teaching children about how the brain works. However, very little is known about children's naive conceptions about the brain. The current study examined these representations, by asking 6-10 year-old children ( = 257) and adults ( = 38) to draw a brain and the inside of a belly as a control drawing. The drawings were scored using a content analysis and a list of graphic indicators was derived. First, all the graphic indicators used in the brain drawings were different from those used in the belly drawings, suggesting that children are able to distinguish these two organs. Second, with age, children depict (i) an increasing number of indicators, (ii) more complex indicators, (iii) indicators that are more anatomically correct, to depict the brain. There is an important evolution between 6 and 8 years-old but also between 10 years-old and adults. These results are discussed in relation to children's metacognitive knowledge and to their implications for neuroeducation.
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http://dx.doi.org/10.3389/fpsyg.2022.951784 | DOI Listing |
Neurology
January 2025
Leonard Davis School of Gerontology, University of Southern California, Los Angeles.
Background And Objectives: Cerebrovascular reactivity (CVR) represents the ability of cerebral blood vessels to regulate blood flow in response to vasoactive stimuli and is related to cognition in cerebrovascular and neurodegenerative conditions. However, few studies have examined CVR in the medial temporal lobe, known to be affected early in Alzheimer disease and to influence memory function. We aimed to examine whether medial temporal CVR is associated with memory function in older adults with and without mild cognitive impairment (MCI).
View Article and Find Full Text PDFBackground: Biomarkers, such as blood p-tau181, p-tau217, and p-tau231, have been created and verified to mirror the pathophysiology of tau and amyloid-β (Aβ) in the brain . Sleep spindles are known to contribute to memory consolidation and generalization and may therefore be a promising biomarker in preclinical Alzheimer's Disease (AD) . The present study investigated the relationship between sleep spindles and p-tau levels in cognitively healthy older African Americans.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Memory and Aging Center, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Background: Growth Differentiation Factor 15 (GDF15) is a TGF-beta superfamily protein upregulated during immune-mediated stress responses. Peripheral GDF15 is linked to adverse aging across organ systems including the brain. Immune dysregulation is implicated in frontotemporal dementia (FTD) pathogenesis.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Memory and Aging Center, UCSF Weill Institute for Neurosciences, San Francisco, CA, USA.
Background: Early onset dementia (EOD) affects people at the peak of their personal and professional responsibilities and economic productivity. Alzheimer's disease (AD) and Frontotemporal Dementia (FTD) are the most common EOD etiologies in Non-Latinx White adults (NLW). Black and Latinx older adults bear a disproportionate burden of dementia compared to NLW, likely due to vulnerabilities that confer increased risk, such as cardiovascular factors, socioeconomic stressors, and structural racism.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Kansas Alzheimer's Disease Research Center, Fairway, KS, USA.
Background: Plasma biomarkers show a promising future to improving the quality of diagnosing Alzheimer's Disease (AD). However, blood processing procedures should be considered when measuring plasma biomarkers. Here we investigate brain-derived neurotrophic factor (BDNF) in platelet-rich and platelet-poor plasma.
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