Stylized tubes are an established visualization primitive for line data as encountered in many scientific fields, ranging from characteristic lines in flow fields, fiber tracks reconstructed from diffusion tensor imaging, to trajectories of moving objects as they arise from cyber-physical systems in many engineering disciplines. Typical challenges include large data set sizes demanding for efficient rendering techniques as well as a large number of attributes that cannot be mapped simultaneously to the basic visual attributes provided by a tube-based visualization. In this work, we tackle both challenges with a new on-tube visualization approach. We improve recent work on high-quality GPU ray casting of Hermite spline tubes supporting ambient occlusion and extend it by a new layered procedural texturing technique. In the proposed framework, a large number of data set attributes can be mapped simultaneously to a variety of glyphs and plots that are embedded in texture space and organized in layers. Efficient rendering with minimal data transfer is achieved by generating the glyphs procedurally and drawing them in a deferred shading pass. We integrated these techniques in a prototype visualization tool that facilitates flexible mapping of data set attributes to visual tube and glyph attributes. We studied our approach on a variety of example data from different fields and found it to provide a highly adaptable and extensible toolbox to quickly craft tailor-made tube-based trajectory visualizations.
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http://dx.doi.org/10.1109/TVCG.2022.3209400 | DOI Listing |
Anal Chem
January 2025
Separation Science Group, Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4bis, B-9000 Ghent, Belgium.
Addressing the global challenge of ensuring access to safe drinking water, especially in developing countries, demands cost-effective, eco-friendly, and readily available technologies. The persistence, toxicity, and bioaccumulation potential of organic pollutants arising from various human activities pose substantial hurdles. While high-performance liquid chromatography coupled with high-resolution mass spectrometry (HPLC-HRMS) is a widely utilized technique for identifying pollutants in water, the multitude of structures for a single elemental composition complicates structural identification.
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
Institute of Materials for Electronics and Energy Technology (i-MEET), Department of Materials Science and Engineering, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Martensstraße 7, 91058 Erlangen, Germany.
Emerging photovoltaics for outer space applications are one of the many examples where radiation hard molecular semiconductors are essential. However, due to a lack of general design principles, their resilience against extra-terrestrial high-energy radiation can currently not be predicted. In this work, the discovery of radiation hard materials is accelerated by combining the strengths of high-throughput, lab automation and machine learning.
View Article and Find Full Text PDFJ Phys Chem A
January 2025
Liaoning Key Laboratory of Manufacturing System and Logistics Optimization, Shenyang 110819, China.
Artificial intelligence technology has introduced a new research paradigm into the fields of quantum chemistry and materials science, leading to numerous studies that utilize machine learning methods to predict molecular properties. We contend that an exemplary deep learning model should not only achieve high-precision predictions of molecular properties but also incorporate guidance from physical mechanisms. Here, we propose a framework for predicting molecular properties based on data-driven electron density images, referred to as D3-ImgNet.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
College of Public Health, University of Kentucky, Lexington, KY, USA.
Background: Brain arteriolosclerosis (B-ASC) is a pathologic hallmark characterized by dysmorphic brain arteriolar wall thickening. B-ASC is a common finding at autopsy in aged persons - some degree of B-ASC is seen in >80% of brains beyond age 80 years - and is associated with cognitive impairment. Hypertension and diabetes are widely recognized as risk factors for B-ASC.
View Article and Find Full Text PDFBackground: Single-nucleus RNA sequencing (snRNAseq) allows for the dissection of the cell type-specific transcriptional profiles of tissue specimens. In this study, we compared gene expression in multiple brain cell types in brain tissue from Alzheimer disease (AD) cases with no or other co-existing pathologies including Lewy body disease (LBD) and vascular disease (VaD).
Method: We evaluated differential gene expression measured from single nucleus RNA sequencing (snRNAseq) data generated from the hippocampus region tissue donated by 11 BU ADRC participants with neuropathologically confirmed AD with or without a co-existing pathology (AD-only = 3, AD+VaD = 6, AD+LBD = 2).
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