This article identified rates of traumatic brain injury (TBI) and recidivism among people incarcerated or exiting incarceration in Indiana using data from different sectors of the incarcerated population. This article was a collaboration between the rehabilitation hospital of Indiana and both the Indiana Department of Correction (IDOC) and the problem-solving courts of Marion County, resulting in two distinct screening samples. Participants in the IDOC sample ( = 2,791) were screened over a period of 2 years and 4 months. Participants in the specialty courts sample ( = 189) were screened between August and October 2016. The rates of moderate-to-severe TBI in the samples were highly variable and ranged from 13% to 86%, higher than in the general population. Recidivism rates for those with TBI were significantly higher than among participants without TBI at 6 and 12 months postrelease. Formerly incarcerated people from the IDOC sample reporting a moderate-to-severe TBI were nearly two times more likely to return to incarceration within 1 year of release.
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http://dx.doi.org/10.1089/jchc.21.01.0003 | DOI Listing |
Alzheimers Dement
December 2024
Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Introduction: Alzheimer's disease (AD), primary age-related tauopathy (PART), and chronic traumatic encephalopathy (CTE) all feature hyperphosphorylated tau (p-tau)-immunoreactive neurofibrillary degeneration, but differ in neuroanatomical distribution and progression of neurofibrillary degeneration and amyloid beta (Aβ) deposition.
Methods: We used Nanostring GeoMx Digital Spatial Profiling to compare the expression of 70 proteins in neurofibrillary tangle (NFT)-bearing and non-NFT-bearing neurons in hippocampal CA1, CA2, and CA4 subregions and entorhinal cortex of cases with autopsy-confirmed AD (n = 8), PART (n = 7), and CTE (n = 5).
Results: There were numerous subregion-specific differences related to Aβ processing, autophagy/proteostasis, inflammation, gliosis, oxidative stress, neuronal/synaptic integrity, and p-tau epitopes among these different disorders.
Clin Transl Med
January 2025
Institute of Clinical Pharmacy, Jining First People's Hospital, Shandong First Medical University, Jining, P.R. China.
Cureus
November 2024
Medical Engineering, Cardiff University School of Engineering, Wales, GBR.
Objectives: Pediatric head and spinal traumas are challenging for healthcare professionals due to their potential for severe consequences. Understanding optimal management methods is crucial to prevent complications and improve outcomes. Head and spinal injuries are common in children, with falls and motor vehicle collisions as the leading causes.
View Article and Find Full Text PDFArch Razi Inst
June 2024
Nephrology and Urology Research Center, Clinical Science Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
In this case report, we present a 63-year-old man with a history of diabetes mellitus and kidney transplantation who was diagnosed with nasal myiasis. The patient presented with symptoms of nasal myiasis infestation, including epistaxis, nasal obstruction, nasal discharge, and the presence of larvae. The patient had risk factors for poor wound healing, such as hyperglycemia, and the presence of diabetes mellitus, hypertension, and kidney transplantation indicated the presence of predisposing factors for myiasis.
View Article and Find Full Text PDFCrit Care
December 2024
Brain Physics Laboratory, Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Background: Entropy quantifies the level of disorder within a system. Low entropy reflects increased rigidity of homeostatic feedback systems possibly reflecting failure of protective physiological mechanisms like cerebral autoregulation. In traumatic brain injury (TBI), low entropy of heart rate and intracranial pressure (ICP) predict unfavorable outcome.
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