Many chemical and biological processes involve phase separation; however, controlling this is challenging. Here, we demonstrate local phase separation using optical tweezers in a thermo-responsive ionic liquid/water solution. Upon near-infrared laser irradiation, a single droplet is formed at the focal spot. The droplet has a core consisting of highly concentrated ionic liquid. The mechanism of the core-shell droplet formation is discussed in view of the spatial distribution of optical and thermal potentials.
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