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Clinical, laboratory, and orbital imaging features of giant cell arteritis in comparison to non-arteritic anterior ischemic optic neuropath: a single center case series.
Front Ophthalmol (Lausanne)
December 2024
Department of Ophthalmology & Visual Sciences, School of Medicine, Washington University in St. Louis, St Louis, MO, United States.
Background: Giant cell arteritis (GCA) is the most common vasculitis in patients older than 50 years and is considered a "do not miss" diagnosis. However, it remains a diagnostic challenge given overlapping clinical syndromes such as non-arteritic anterior ischemic optic neuropathy (NAION) and poorly explored imaging findings.
Materials And Methods: In this retrospective study between the time period of January 2013 and December 2021, a total of 13 consecutive patients with a pathological diagnosis of GCA and 8 patients with clinical diagnosis of NAION were isolated.
FROM DIALYSIS TO HALLUCINATIONS: CHARLES BONNET SYNDROME AS A SEQUELA OF BILATERAL NON-ARTERITIC ANTERIOR ISCHEMIC OPTIC NEUROPATHY.
Psychiatr Danub
December 2024
Department of Psychiatry and Mental Health, Hospital de Santa Maria.
Impact of Lipid Parameters on Visual Acuity Change in Non-Arteritic Anterior Ischemic Optic Neuropathy.
Clin Ophthalmol
December 2024
Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Purpose: To assess the potential influence of serum biochemical factors, specifically lipid profile parameters, on visual outcomes in patients with non-arteritic anterior ischemic optic neuropathy (NAION).
Patients And Methods: All patients diagnosed with NAION at Rajavithi Hospital between 1 January 2011 and 31 December 2020 were retrospectively reviewed. The primary outcome was defined as visual recovery, measured by an improvement of at least 0.
Once-weekly semaglutide doubles the five-year risk of nonarteritic anterior ischemic optic neuropathy in a Danish cohort of 424,152 persons with type 2 diabetes.
Int J Retina Vitreous
December 2024
Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Background: Nonarteritic anterior ischemic optic neuropathy (NAION) is an untreatable condition often causing severe and irreversible visual loss in the affected eye. As it has recently been implied that the use of semaglutide associates with NAION, the aim of the present study was to evaluate this risk prospectively in all persons with type 2 diabetes (T2D) in Denmark.
Methods: In a five-year longitudinal cohort study, we identified all persons with T2D in Denmark (n = 424,152) between 2018 and 2024.
Optic nerve sheath enhancement on orbital MRI in giant cell arteritis.
Br J Ophthalmol
December 2024
Medicine - Rheumatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Background: Differentiating arteritic anterior ischaemic optic neuropathy (A-AION) due to giant cell arteritis (GCA) from non-arteritic anterior ischaemic optic neuropathy (NA-AION) may pose a diagnostic challenge. Our study aimed to assess the use of standard orbital MRI in distinguishing ocular manifestations of GCA from NA-AION.
Methods: This study included 25 consecutive patients (11 GCA, 14 NA-AION) who underwent contrast-enhanced orbital MRIs within 3 months of symptom onset.
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