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Early Days in the Hunt Laboratory at UVA, 1969 to 1980.
Mol Cell Proteomics
December 2024
Saint Joseph's University, Philadelphia, Pennsylvania, USA.
Arriving at the University of Virginia in the autumn of 1969, Donald Hunt began his 50+ year career in academics with the study of organometallic chemistry, on which he had done his PhD thesis work, and mass spectrometry, to which he was introduced while a postdoc in Klaus Biemann's laboratory at the Massachusetts Institute of Technology. In the 1970s, Hunt's lab pioneered the use of negative chemical ionization (CI) to enhance sensitivity for studying organic molecules, developed a system for simultaneously obtaining positive and negative CI spectra to augment structure elucidation, and built a prototype triple quadrupole instrument so effective at collisional dissociation that its commercial counterpart became the analytical instrument of choice for mixture analysis for the next decade and beyond. Foreseeing that the future lay in the analysis of biological molecules, by the end of the decade Hunt shifted his focus to peptides.
View Article and Find Full Text PDFTribute to Klaus Eichmann, Editor-in-Chief of Cellular and Molecular Life Sciences.
Cell Mol Life Sci
September 2022
Institut National de la Santé et de la Recherche Médicale, Paris Brain Institute, Paris, France.
Pushing the limits of flash photolysis to unravel the secrets of biological electron and proton transfer.
Photochem Photobiol Sci
September 2022
Institut de Biologie Structurale, 38044, Grenoble, France.
Time-resolved absorption spectroscopy is a powerful tool to unravel biological functions and has been a key technology for elucidating the working of electron transfer chains in photosynthesis or photorepair of UV-damaged DNA. Both of these areas have seen important contributions from laboratories all over the world, not the least of them stemming from the ingenious technical advances described by Klaus Brettel, first at the Technical University of Berlin (Germany), and later at the Atomic Energy Agency in Saclay (France). Now, after more than forty years of tireless scientific activity, Klaus is approaching retirement and this collection gathers together tributes in the form of scientific contributions from colleagues along the way, covering a spectrum of topics as diverse as photosynthesis, light-induced DNA repair, electron and proton transfer in light signalling, flavin based photo-enzymology, fluorescent marker photophysics, synthetic models and modelisation, delicate sample transient absorption spectroscopy.
View Article and Find Full Text PDFKlaus Apel (1942-2017): a pioneer of photosynthesis research.
Photosynth Res
August 2018
Hegemann Lab, Institute of Biology, Experimental Biophysics, Humboldt-Universität zu Berlin, Invalidenstraße 42, 10115, Berlin, Germany.
We present here a Tribute to Klaus Apel (1942-2017), a photosynthesis pioneer-an authority on plant molecular genetics-in five parts. The first section is a prologue. The second section deals with a chronological discussion of Apel's research life, prepared by the editor Govindjee; it is based on a website article at the Boyce Thompson Institute (BTI) by Patricia Waldron ( https://btiscience.
View Article and Find Full Text PDFThe Marshall Klaus Research Award and Tribute to a Trailblazing Neonatologist.
J Perinatol
March 2018
Department of Pediatrics, Division of Neonatology, Vanderbilt University, Nashville, TN, USA.
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