Background: Endometriosis usually presents in the pelvic region, but extragenital endometriosis may occur in almost every other organ. Umbilical endometriosis represents 0.5-1.2 % of all cases of endometriosis, and can further be divided into primary and secondary presentation, occurring in women without and with umbilical scars, respectively. Common clinical presentation is periodic pain, swelling and bleeding.
Case Presentation: A woman in her thirties without abdominal scars presented with a painful umbilical nodule with spontaneous periodic bleeding and swelling. MRI and fine needle aspiration cytology suggested umbilical endometriosis, and this diagnosis was confirmed histologically after surgical excision.
Interpretation: Umbilical endometriosis should be considered in cases of umbilical nodules with cyclic variation of symptoms. It is treated with simple surgical excision, and histopathology confirms the diagnosis. Approximately 20 % of patients also present with pelvic endometriosis, but diagnostic laparoscopy is only recommended if symptoms of pelvic endometriosis are also present.
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http://dx.doi.org/10.4045/tidsskr.22.0126 | DOI Listing |
BMJ Case Rep
January 2025
Pulmonary Medicine, K S Hegde Medical Academy, Mangaluru, Karnataka, India
A nulliparous woman in her late 30s with a history of pericardial patch repair for atrial septal defect and completed treatment for pulmonary tuberculosis 9 years ago presented with chest pain, breathlessness and abdominal pain. Radiological imaging revealed right-sided pneumothorax, pneumopericardium and pneumoperitoneum for which an intercostal drain (ICD) was placed. A contrast-enhanced CT of the abdomen showed a distal stomach perforation, which was managed conservatively.
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February 2025
Faculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.
Int Med Case Rep J
December 2024
Gynecology and Obstetric Department, Kabul University of Medical Science, Shahr Ara University Hospital, Kabul, Afghanistan.
Primary umbilical endometriosis is a rare condition in which there is endometrial glands and stroma in the umbilicus. Primary umbilical endometriosis is also called villar's nodule. This condition is a diagnostic challenge, the pathophysiology of the disease is not well defined and should be considered in all other pathologies of the umbilicus.
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September 2024
Department of Surgery, University of Calabar/University of Calabar Teaching Hospital, Calabar, Nigeria.
Proc Natl Acad Sci U S A
September 2024
Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, United Kingdom.
Endometriosis negatively impacts the health-related quality of life of 190 million women worldwide. Novel advances in nonhormonal treatments for this debilitating condition are desperately needed. Macrophages play a vital role in the pathophysiology of endometriosis and represent a promising therapeutic target.
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