Hepatitis E - epidemiology and clinical course in the largest cohort in the Czech Republic.

Arch Med Sci

Department of Infectious Diseases, Faculty of Medicine, Masaryk University, Brno, Czech Republic.

Published: August 2022

Introduction: The majority of hepatitis E (HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic.

Methods: A retrospective analysis of 173 patients with HE.

Results: At least 90% of cases were autochthonous (HEV-3 genotype). Seventeen patients were treated with ribavirin. Five underwent liver transplants because of fulminant HE. We noted neurological symptomatology in 9 cases. Six patients developed chronic HE.

Conclusions: There is a possibility of severe health complications caused by the hepatitis E virus in the Czech Republic.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479705PMC
http://dx.doi.org/10.5114/aoms/152338DOI Listing

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