Five potential sites nominated for the Nation's first geologic repository for disposing of nuclear waste are evaluated using multiattribute utility analysis. The analysis was designed to aid the Department of Energy in its selection of 3 sites for characterization, a detailed data-gathering process that will involve the construction of exploratory shafts for underground testing and that may cost as much as $1 billion per site. The analysis produced insights into the relative advantages and disadvantages of the nominated sites and clarified current uncertainties regarding repository performance.
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http://dx.doi.org/10.1111/j.1539-6924.1987.tb00981.x | DOI Listing |
Heliyon
January 2025
Department of Mathematics and Statistics, International Islamic University Islamabad, Pakistan.
Improving human health and comfort in buildings requires efficient temperature regulation. Temperature control system has a significant contribution in minimizing the impact of climate change. Temperature control system is used in industry to control temperature.
View Article and Find Full Text PDFAnal Chem
January 2025
Protein Analytical Chemistry, Genentech, A Member of the Roche Group, 1 DNA Way, South San Francisco, California 94080, United States.
New peak detection (NPD) is a significant component of the multiattribute method (MAM) for MS use to facilitate the detection of quality attributes exhibiting abnormal ratio changes, vanishing attributes, or newly emerging attributes. However, challenges remain to get a balanced sensitivity and minimize false positives in NPD. In this study, we have developed a robust NPD and identification method to enhance sensitivity 10-fold (0.
View Article and Find Full Text PDFAlzheimers Dement (N Y)
November 2024
Department of Neurology Biologic Sciences Division, Healthy Aging and Alzheimer's Research Care Center University of Chicago Chicago Illinois USA.
Introduction: Measurements of health-related quality of life (HRQoL) are important for capturing disease impact beyond physical health and relative to other diseases but have rarely been assessed in primary progressive aphasia (PPA).
Methods: HRQoL was characterized overall, by sex and subtype in PPA ( = 118) using the Health Utilities Index-2/3 (HUI2/3). Multiple linear regression assessed associations between HRQoL and language severity.
BMC Health Serv Res
January 2025
College of Health and Medicine, Menzies Institute for Medical Research, University of Tasmania, 17 Liverpool Street, Hobart, TAS, Australia.
Objective: To evaluate the impact of absolute cardiovascular risk counselling on quality-of-life indices within a chest pain clinic.
Data Sources And Study Setting: Primary data was collected at the Royal Hobart Hospital, Australia, between 2014 and 2020.
Study Design: Patients attending an Australian chest pain clinic were randomised into a prospective, open-label, blinded-endpoint study over a minimum 12-months follow-up.
Sci Rep
December 2024
State Key Laboratory of Hydraulics and Mountain River Engineering, College of Water Resource and Hydropower, Sichuan University, Chengdu, 610065, China.
Addressing the need to harmonize environment conservation and sustainable economic development within the Yellow River Basin (YRB) requires a profound comprehension of the spatiotemporal dynamics of urban ecosystem resilience. This study developed an index system utilizing the resistance-adaptability-recovery framework to measure these dynamics. By applying the advanced multi-attribute boundary area comparison method and a spatial autocorrelation model, we investigated the spatiotemporal variations and spatial correlation patterns of urban ecological resilience across the YRB.
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