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Complete resection of large-cell neuroendocrine and hepatocellular carcinoma of the liver: A case report. | LitMetric

Complete resection of large-cell neuroendocrine and hepatocellular carcinoma of the liver: A case report.

World J Clin Cases

Department of Pathology, Pusan National University School of Medicine, Biomedical Research Institute, Pusan National University Hospital, Busan 49241, South Korea.

Published: August 2022

AI Article Synopsis

Article Abstract

Background: Combined tumors comprising large-cell neuroendocrine carcinoma and hepatocellular carcinoma have been rarely reported in the literature.

Case Summary: We report a case of a 73-year-old woman with chronic hepatitis B suspected to have a malignant hepatic mass (segment 3; size, 4.5 cm) and lymph node metastasis based on computed tomography and magnetic resonance imaging. Despite being Child-Pugh class A, esophageal varices were present. She underwent left lateral sectionectomy and lymph node dissection. Pathological examination revealed a collision tumor consisting of large-cell neuroendocrine (90%) and hepatocellular (10%) carcinomas. The combined carcinoma had metastasized to one of the three lymph nodes excised. The patient recovered without any postoperative complications and was discharged in good condition on postoperative day 13. Adjuvant chemotherapy was not performed. No recurrence occurred during a follow-up period of 24 mo.

Conclusion: To improve the therapeutic management of combined tumors in the liver, it is necessary to discuss each clinical experience and consider an appropriate method for the preoperative diagnosis and treatment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403669PMC
http://dx.doi.org/10.12998/wjcc.v10.i23.8277DOI Listing

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