AI Article Synopsis
- Catheter ablation is a common treatment for atrial fibrillation (AF), but many patients experience a recurrence of the condition after the procedure.
- Researchers developed a predictive model called HASBLP score to identify which patients are more likely to relapse, allowing for tailored treatment plans.
- In a study tracking over 1,000 patients for two years, they found that factors like AF history, age, snoring, body mass index, left atrial size, and persistent AF significantly influenced recurrence, and the new model outperformed existing scoring systems.
Article Abstract
Background: At present, catheter ablation is an effective method for rhythm control in patients with atrial fibrillation (AF). However, AF recurrence is an inevitable problem after catheter ablation. To identify patients who are prone to relapse, we developed a predictive model that allows clinicians to closely monitor these patients and treat them with different personalized treatment plans.
Materials And Methods: A total of 1,065 patients who underwent AF catheter ablation between January 2015 and December 2018 were consecutively included in this study, which examines the results of a 2-year follow-up. Patients with AF were divided into development cohort and validation cohort. Univariate and multivariate analyses were carried out on the potential risk factors. Specific risk factors were used to draw the nomogram according to the above results. Finally, we verified the performance of our model compared with CHADS2 and CHADS-Vasc scores by receiver operating characteristic (ROC) curve and calibration curve and plotted the decision analysis curve (DAC).
Results: A total of 316 patients experienced AF recurrence. After univariate and multivariate analyses, AF history (H), age (A), snoring (S), body mass index (BMI) (B), anteroposterior diameter of left atrial (LA) (L), and persistent AF (P) were included in our prediction model. Our model showed a better performance compared with CHADS2 and CHA2DS2-Vasc scores, and the area under ROC curve (95%CI) was 0.7668 (0.7298-0.8037) vs. 0.6225 (0.5783-0.6666) and 0.6267 (0.5836-0.6717).
Conclusion: We established a nomogram (HASBLP score) for predicting AF recurrence after the first catheter ablation at a 2-year follow-up, which can be used as a tool to guide future follow-up of patients. However, its usefulness needs further validation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497656 | PMC |
| http://dx.doi.org/10.3389/fcvm.2022.934664 | DOI Listing |
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