AI Article Synopsis
- The prevalence of heart failure (HF) is rising, especially among older populations, but about 10% of HF patients are under 50 years old, showing a concerning trend in younger adults.
- Factors leading to HF in younger individuals include genetic issues, premature vascular problems, metabolic stress, harmful reactions to certain substances, and myocarditis, which are often overlooked.
- Increasing risk factors like obesity, diabetes, and hypertension are also significantly contributing to the development of HF in younger patients, indicating a need for targeted preventive measures.
Article Abstract
The prevalence of Heart failure (HF) is increasing with the aging of the population but it is estimated that 10% of HF patients are younger than 50 years-old. HF development in this population is characterized with a fast-growing prevalence, and important disparities according to underlying etiologies or gender. These observations highlight the need to identify specific and preventable factors in these patients, a topic that is under-studied. Here we provide an overview of trends in prevalence of major etiologies leading to HF in young subjects, including genetic factors associated with cardiomyopathies, premature vascular dysfunction and related ischemia, metabolic stress, cardio-toxic responses to different agents, and myocarditis. We also highlight the increasing influence of major risk factors that are driving HF in younger patients, such as obesity, diabetes or arterial hypertension.
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| http://dx.doi.org/10.1016/j.tcm.2022.09.005 | DOI Listing |
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