Cytochrome P450 Gene, , Is Involved in the Resistance to Cyantraniliprole in .

is an important agricultural sucking pest, and it develops serious resistance to various insecticides. Although cytochrome P450 was involved in the resistance to cyantraniliprole, limited studies have been conducted on . In the present study, piperonyl butoxide significantly increased the toxicity of cyantraniliprole. P450 activities in two resistant populations were 1.97- and 2.17-fold higher than that in the susceptible population. Among 79 P450 genes, expressions in two resistant populations were 3.08- and 3.67-fold higher than that in the susceptible population. When was knocked down, the toxicity of cyantraniliprole increased significantly. The LC value of cyantraniliprole to the line overexpressing increased 7.34-fold. The content of cyantraniliprole was decreased by 25.74 ± 4.27% after mixing with and for 2 h. These results suggested that the overexpression of was likely involved in the resistance to cyantraniliprole in .