AI Article Synopsis
- Immunotherapy is a new treatment that helps people with metastatic melanoma, and researchers want to find out what makes it work better for some patients.
- Studies show that the gut microbiome (the bacteria in our stomach) might affect how well the immunotherapy works and if side effects happen.
- The review talks about ways to change the gut microbiome, like using probiotics, changing diets, or a process called fecal microbiota transplantation, to help improve treatment outcomes.
Article Abstract
For patients with metastatic melanoma, immunotherapy agents represent a promising treatment option, and researchers are actively seeking to identify factors that may predict a favorable response in patients. Recent studies have elucidated possible associations between the gut microbiome and the effects of immunotherapy, where variations in the gut microbiome may influence treatment response and frequency of adverse effects. In this clinical review, we describe the current literature related to the gut microbiome in the setting of immunotherapy, and we provide an overview of interventions under investigation that may modulate the gut microbiome. These interventions include fecal microbiota transplantation, probiotics, and dietary modifications.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588106 | PMC |
| http://dx.doi.org/10.1007/s13555-022-00810-1 | DOI Listing |
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