Urgent desensitization for severe amiodarone intolerance with a 12-step protocol.

A 68-year-old man with severe nonischemic cardiomyopathy presented with cardiogenic shock and electrical storm. The patient had recently experienced a severe skin reaction to amiodarone and did not respond to alternative antiarrhythmic therapies. He underwent an emergent desensitization protocol and was able to tolerate amiodarone within 12 h. This was effective at suppressing electrical storm and did not lead to any further allergic or hemodynamic issues.