Antecedent factors which influence adult engagement with nature are underexplored given the human health benefits strongly associated with nature exposure. Formative pathways and impediments to nature contact merit understanding as they may contribute to later-life health disparities. We probed experiential pathways and attitudes toward nature engagement among adults purposefully sampled across U.S. regions, age, race/ethnicity, and urbanicity through semi-structured focus group discussions. The research aims were to explore entryways and barriers to experiencing nature and learn how natured and built environments compete in influencing human-nature relationships. Sessions were recorded, transcribed, and analyzed following Braun and Clarke's phases of thematic analysis. Qualitative content analysis of discussions identified three principal themes: 1) formative influences promoting adult nature engagement (i.e., persons/organizations and places of origin), 2) detractors from nature engagement (i.e., perceptual, material, and physical barriers), and 3) role of current setting (i.e., natural and built environments) shaping nature-seeking relationships. We found experiential factors that included early life exposures outdoors, personal mentorship, and organizational affiliation to be highly influential in socializing individuals to nature and in soldering attachment to nature which manifests into adulthood. In contrast, changing demographics and childhood, inequity, social dynamics, metropolitan growth, urban renewal explained alienation from nature. These findings emphasize the importance of efforts to expand opportunities for nature contact, especially for youth living in economically challenged urban areas, which go beyond increasing greenspace to encompass mentoring partnerships for gaining skills and comfort outdoors and redesign of safe natured spaces within cities for hands-on learning and discovery.
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Sensors (Basel)
December 2024
Department of Information Convergence Engineering, Pusan National University, Busan 46241, Republic of Korea.
Dialogue systems must understand children's utterance intentions by considering their unique linguistic characteristics, such as syntactic incompleteness, pronunciation inaccuracies, and creative expressions, to enable natural conversational engagement in child-robot interactions. Even state-of-the-art large language models (LLMs) for language understanding and contextual awareness cannot comprehend children's intent as accurately as humans because of their distinctive features. An LLM-based dialogue system should acquire the manner by which humans understand children's speech to enhance its intention reasoning performance in verbal interactions with children.
View Article and Find Full Text PDFPathogens
December 2024
Immunology and Infectious Diseases Program, Division of BioMedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL A1B 3V6, Canada.
Natural killer (NK) and CD8 T cell function is compromised in human immunodeficiency virus type 1 (HIV-1) infection by increased expression of inhibitory receptors such as TIGIT (T cell immunoreceptor with Ig and ITIM domains). Blocking inhibitory receptors or their ligands with monoclonal antibodies (mAb) has potential to improve antiviral immunity in general and facilitate HIV eradication strategies. We assessed the impact of TIGIT engagement and blockade on cytotoxicity, degranulation, and interferon-gamma (IFN-γ) production by CD8 T cells from persons living with HIV (PLWH).
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Department of Biochemistry, College of Natural Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea.
Recent advances in cryo-electron microscopy (cryo-EM) have facilitated the high-resolution structural determination of macromolecular complexes in their native states, providing valuable insights into their dynamic behaviors. However, insufficient understanding or experience with the cryo-EM image processing parameters can result in the loss of biological meaning. In this paper, we investigate the dihydrolipoyl acetyltransferase (E2) inner core complex of the pyruvate dehydrogenase complex (PDC) and reconstruct the 3D maps using five different symmetry parameters.
View Article and Find Full Text PDFChildren (Basel)
December 2024
National Health Commission Key Laboratory of Reproductive Health, Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing 100191, China.
Background: The aim of this study was to explore the association between long-term exposure to particulate matter with an aerodynamic diameter <2.5 μm (PM) and its components and severe obesity in children and adolescents.
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Children (Basel)
November 2024
School of Rural Health, Monash University, Melbourne, VIC 3800, Australia.
Mental health concerns among youth represent a critical global public health issue. Research has found that youth with mental health concerns are often reliant on their caregivers while being isolated from peers. Guided by the recovery model of mental health care, this study investigates the often-overlooked role of caregivers in fostering 'connectedness' in youth; Methods: Semi-structured interviews were conducted with nine caregivers of youth with mental health issue; Results: Thematic analysis underscored three tasks in the role of caregivers in promoting connectedness in youth: (a) understanding the nature and quality of social networks, (b) supporting readiness to engage in social relationships, and (c) promoting their youth's social problem solving and self-efficacy; Discussion: These tasks highlight the complex dialectics faced by caregivers in supporting youth recovery.
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