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Renovascular hypertension secondary to Takayasu's arteritis in a child: Case report. | LitMetric

AI Article Synopsis

  • Takayasu arteritis (TA) is a chronic disease that causes inflammation of the arteries, particularly the aorta, leading to complications like hypertension and heart issues.
  • A 12-year-old girl with TA experienced dyspnea and growth issues and was successfully treated with balloon angioplasty after managing her inflammation and high blood pressure, but she later faced re-stenosis and needed a second procedure.
  • It's important to consider TA as a cause of secondary hypertension in young patients, and treating the associated arterial problems can be done with minimal complications.

Article Abstract

Introduction: Takayasu arteritis (TA) is a chronic inflammatory arteriopathy of unknown etiology that affects the aorta and its branches. Inflammation leads to arterial stenosis, thrombosis, and aneurysm formation. Management strategies for TA include medical therapy and revascularization procedures after inflammation is controlled.

Presentation Of The Case: We report the case of a 12-year-old female patient, who presented with dyspnea and growth retardation. Initial clinical and radiological evaluations revealed hypertension and congestive heart failure. After controlling the inflammatory phase of the disease and blood pressure partially (with three antihypertensive agents), the patient underwent percutaneous balloon angioplasty of both renal arteries, with angiographic and clinical success. At the 2-year follow-up, she presented with re-stenosis of the right renal artery and progression of the supra-renal aortic stenosis. She was subjected to a second balloon angioplasty of the right renal artery and aortic balloon angioplasty.

Discussion: After controlling the inflammatory phase of the disease, stenotic and/or aneurysmal lesions can be addressed. Percutaneous revascularization of renal arteries is reasonable for patients with hemodynamically significant renal artery stenosis.

Conclusion: TA with renal involvement must be considered as an etiologic factor for secondary hypertension in young patients, even if there is no blood pressure difference between the upper extremities. In this case, renal and aortic stenosis were performed with low perioperative morbidity.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486410PMC
http://dx.doi.org/10.1016/j.amsu.2022.104247DOI Listing

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