Experimental Phaeohyphomycosis of .

Originally considered to be a plant pathogen, reports of phaeohyphomycosis due to () in animals and humans are increasing. However, studies on the pathogenesis, virulence, and epidemiology of have rarely been discussed. In the present study, BALB/c mice were experimentally inoculated with suspension by different routes and the course of infection was evaluated. In addition, the in vitro antifungal susceptibility of against six commonly used antifungals was evaluated using the microdilution method. Inoculation resulted in skin lesions in animals inoculated intraperitonially and subcutaneously. Infection was confirmed by both mycological and histopathologic examination. spores and hyphae were detected in the histopathologic sections stained with hexamine silver staining. In addition, voriconazole (VRC) demonstrated greater activity against when compared to the other antifungals, whereas fluconazole (FLC) was the least active antifungal with a minimum inhibitory concentration (MIC) range of 8-16 μg/mL. Further studies are necessary to understand the pathogenicity of and uncover the mystery of this fungus.