Targeted fortification with human milk analysis: An opportunity for innovation.

Semin Fetal Neonatal Med

Division of Neonatology, Department of Pediatrics, MetroHealth Medical Center, Cleveland, OH, USA; Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, OH, USA. Electronic address:

Published: October 2022

Human milk's variable macronutrient composition is a necessary consideration when caring for very low birthweight infants. Targeted fortification is the practice of fortifying human milk using its known composition from human milk analysis, rather than its assumed macronutrient values. Utilization of human milk analyzers to measure the protein, fat, lactose, and energy composition within human milk samples has allowed the translation of this practice into the clinical setting. This review discusses the rationale of why targeted fortification is an important practice, what barriers exist in its implementation in the clinical setting, and what research gaps remain to be addressed.

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http://dx.doi.org/10.1016/j.siny.2022.101392DOI Listing

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