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Sensational astrocytes: Mechanotransduction in adult brain function. | LitMetric

Sensational astrocytes: Mechanotransduction in adult brain function.

Neuron

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address:

Published: September 2022

AI Article Synopsis

  • The understanding of how organisms sense their mechanical surroundings is crucial but still not fully clear.
  • In a recent study published in Neuron, Chi and colleagues highlight the importance of the Piezo1 channel found in astrocytes.
  • This channel plays a significant role in adult brain cell formation and cognitive abilities.

Article Abstract

Sensing the mechanical microenvironment is an essential aspect of all life, yet its mechanism remains poorly understood. In this issue of Neuron, Chi et al. reveal the role of astrocyte mechanosensitive Piezo1 channel in adult neurogenesis and cognitive function.

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Source
http://dx.doi.org/10.1016/j.neuron.2022.08.007DOI Listing

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