AI Article Synopsis
- * This innovative method enables hydrogen-atom transfer to alkenes, enhancing organic synthesis techniques.
- * The research includes detailed electroanalytical and spectroscopic analyses that improve our understanding of Co-H formation and its reactivity, leading to the creation of two new hydrofunctionalization reactions for alkenes.
Article Abstract
Hydrogen-atom transfer mediated by earth-abundant transition-metal hydrides (M-Hs) has emerged as a powerful tool in organic synthesis. Current methods to generate M-Hs most frequently rely on oxidatively initiated hydride transfer. Herein, we report a reductive approach to generate Co-H, which allows for canonical hydrogen evolution reactions to be intercepted by hydrogen-atom transfer to an alkene. Electroanalytical and spectroscopic studies provided mechanistic insights into the formation and reactivity of Co-H, which enabled the development of two new alkene hydrofunctionalization reactions.
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| http://dx.doi.org/10.1021/jacs.2c08278 | DOI Listing |
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