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| http://dx.doi.org/10.1097/SCS.0000000000009008 | DOI Listing |
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Late olfactory bulb involvement in COVID-19.
Chem Senses
January 2024
Neuroradiology, Department of Neurosciences, University of Padova, Padova, Italy.
Transient or persistent hypo-anosmia is common in SARS‑CoV‑2 infection but olfactory pathway late-term morphometric changes are still under investigation. We evaluated late olfactory bulb (OB) imaging changes and their correlates with the olfactory function in otherwise neurologically asymptomatic COVID-19 patients. Eighty-three subjects (mean-age 43 ± 14 yr; 54 females; time-interval infection/MRI: 129±68 d) were affected by asymptomatic to mild COVID-19 in 2020 and 25 healthy controls (mean-age 40 ± 13 yr; 9 females) underwent 3T-MRI and olfactory function evaluation through anamnestic questionnaire and Sniffin' Sticks.
View Article and Find Full Text PDFFactors Associated With Persisting Olfactory Dysfunction After COVID-19.
Clin Otolaryngol
January 2025
Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Vienna, Vienna, Austria.
Background: Fortunately, the majority of COVID-19 patients recover from olfactory dysfunction (OD) within the first couple of weeks. However, from approximately 5% up to 20% continue to suffer from OD even more than 1 year after the onset. Nonetheless, factors associated with long-lasting OD are hardly known.
View Article and Find Full Text PDFDeterminants of persistence and recovery of chronic coronavirus disease 2019 chemosensory dysfunction.
J Allergy Clin Immunol
January 2025
Division of Allergy and Clinical Immunology, Jeff and Penny Vinik Center for Allergic Disease Research, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, Mass. Electronic address:
Background: In 2% to 4% of patients, coronavirus disease 2019 (COVID-19) chemosensory dysfunction (CSD) persists beyond 6 months, accounting for up to 4 million people in the United States. The predictors of persistence and recovery require further exploration.
Objective: We sought to define the predictors of recovery and assess the quality of CSD in registry subjects with self-reported persistent smell and taste dysfunction after COVID-19.
Predictive model for postoperative unrecovered olfactory function in CRSwNP patients with olfactory disorder.
Rhinology
December 2024
Department of Otolaryngology-Head and Neck Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Tianhe District, Guangzhou, China; Department of Allergy, The Third Affiliated Hospital of Sun Yat-sen University, Tianhe District, Guangzhou, China; Key Laboratory of Airway Inflammatory Disease Research and Innovative Technology Translation, Guangzhou, China.
Background: Olfactory disorder (OD) is a prevalent and challenging symptom in chronic rhinosinusitis with nasal polyps (CRSwNP). This study aims to investigate the risk factors and develop a predictive model for poor olfactory prognosis in CRSwNP patients with OD after endoscopic sinus surgery (ESS).
Method: Seventy-eight CRSwNP patients with OD who underwent ESS were enrolled.
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