Madelung disease is defined by multiple symmetric fatty accumulations, usually involving the upper trunk, and may sometimes have excessive fat deposition in the prevertebral space. On magnetic resonance imaging (MRI), findings of fat that are hyperintense on T1w and T2w images, may simulate subacute hematoma and mimic cervical spine injury. This is the first reported case of Madelung disease with prevertebral fat deposition mimicking prevertebral hematoma found in cervical spine injury on MRI. Fat suppression techniques are helpful in order to differentiate between these two conditions, which should be taken into consideration during routine clinical practice.
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| http://dx.doi.org/10.1177/19714009221128660 | DOI Listing |
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Article Synopsis
- Madelung disease is a rare metabolic disorder characterized by the abnormal accumulation of adipose tissue in various body areas, primarily affecting individuals from Mediterranean and Eastern European backgrounds, with significantly lower prevalence in Asia.
- The condition is associated with several comorbidities, including diabetes and polyneuropathy, and can lead to severe complications, particularly postoperative hypercoagulability, which increases the risk of serious issues like venous thrombosis and pulmonary embolism.
- This study presents a specific case of type II Madelung disease with significant complications during surgery, while also reviewing existing literature to highlight the disease's features and potential treatment methods, aiming to improve future clinical approaches and reduce surgery-related risks.
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