Most patients with bladder cancer do not respond to ICB targeting of the PD-L1 signaling axis. Our modeling applied a de novo resistance signature to show that tumor-infiltrating myeloid cells promote poor treatment response in a TGFβ-dependent mechanism.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706595 | PMC |
| http://dx.doi.org/10.1158/1535-7163.MCT-22-0130 | DOI Listing |
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