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Inflammatory pseudotumor-like extranodal classic Hodgkin lymphoma manifesting as bowel perforation in acquired immunodeficiency syndrome patient with disseminated leishmaniasis: a case report and approach to differential diagnosis.
J Gastrointest Oncol
December 2024
Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Background: Classic Hodgkin lymphoma (CHL) is an extremely common non-acquired immunodeficiency syndrome (AIDS) defining malignancy and its incidence is rising. CHL is usually present in the lymph node and extranodal involvement is rare. Primary CHL of the gastrointestinal (GI) tract is exceedingly rare.
View Article and Find Full Text PDFSemaglutide as an Adjunctive Therapy to Standard Management for Idiopathic Intracranial Hypertension: A Real-World Data-Based Retrospective Analysis.
medRxiv
November 2024
Montefiore-Einstein Cerebrovascular Research Lab, Albert Einstein College of Medicine, Bronx, NY, USA.
Background: Idiopathic intracranial hypertension (IIH) is a neurological disorder characterized by elevated intracranial pressure, predominantly affecting young women with obesity. This study evaluates the effectiveness of semaglutide as an adjunctive therapy to standard IIH management using real-world data.
Methods: We conducted a retrospective cohort analysis comparing IIH patients receiving semaglutide plus standard therapy versus standard therapy alone.
Invasive Aspergillosis with Cavernous Sinus Thrombosis Following High-Dose Corticosteroid Therapy: A Challenging Case of Rhino-Orbital-Cerebral Mycosis.
J Fungi (Basel)
November 2024
Faculty of Medicine, Pathology Department, Erzincan Binali Yıldırım University, Erzincan 24100, Turkey.
Invasive aspergillosis is a rare but severe fungal infection primarily affecting immunocompromised individuals. The Disease-2019 (COVID-19) pandemic has introduced new complexities in managing aspergillosis due to the widespread use of corticosteroids for treating COVID-19-related respiratory distress, which can increase susceptibility to fungal infections. Here, we present a challenging case of progressive cerebral aspergillosis complicated by cavernous sinus thrombosis (CST) in a 67-year-old male with a history of COVID-19.
View Article and Find Full Text PDFPseudotumoral portal cavernoma: A rare case that challenges diagnosis.
Radiol Case Rep
January 2025
Central Radiology Department, Ibn Sina University Hospital, Rabat, Morocco.
Portal cavernoma cholangiopathy (PCC), also known as portal biliopathy, refers to biliary duct abnormalities caused by extrahepatic portal vein obstruction (EHPVO) and subsequent cavernous transformation of the portal vein. Pseudotumoral portal cavernoma is a specific subtype of PCC characterized by the presence of numerous thin collateral veins that mimic the sheath of the common bile duct (CBD). We present a case of a 42-year-old women with pseudotumoral portal cavernoma secondary to portal vein thrombosis, a complication of myeloproliferative disorder.
View Article and Find Full Text PDFSodium bicarbonate use in the treatment of idiopathic intracranial hypertension.
Eye (Lond)
February 2025
Department of Ophthalmology & Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.
Article Synopsis
- The study examined the effects of sodium bicarbonate (NaHCO) as an add-on treatment to acetazolamide (ACZ) in patients with idiopathic intracranial hypertension (IIH) from 2008 to 2022.
- The results showed that sodium bicarbonate did not significantly improve IIH treatment outcomes compared to ACZ alone, with no major differences in retinal nerve health or visual performance between the two groups.
- However, a significant portion of the treatment group reported reduced side effects from ACZ while on sodium bicarbonate, suggesting it might be beneficial for managing those side effects without affecting treatment effectiveness.
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