Performance is a multidimensional concept and is evaluated by different criteria. Definition and evaluation of research performance are always controversial and may be affected by variable conditions. Therefore, this study aimed to determine the effective trends and driving forces in the future of research performance evaluation. In this qualitative study, the trend analysis through scoping review and interview was done to identify the driving forces affecting the future of research performance evaluation. The scoping review was conducted according to PRISMA-ScR guidelines and searching of the international databases. The interviews were done face-to-face, by telephone, and on social media. MAXQDA version 10 and thematic analysis were used to analyze the interviews and documents. In the scoping review step, a total of 6125 records were found through searching of the international databases and search engines. After removing 869 duplications, the title and abstract of 5256 records were screened. Finally, 42 records (41 English articles and 1 dissertation) were eligible for the study. In the interview step, 248 codes were assigned in nine main categories, 64 subcategories, and 47 dimensions. The trends included social (27 codes), technological (38 codes), economic (30 codes), environmental (5 codes), and political (44 codes) dimensions. Then, acquired information from two steps was synthesized, and the effective social, technological, economic, environmental, and political trends and driving forces were identified. The results showed that various social, technological, economic, environmental, and political factors and indicators must be included and normalized in the national and international research performance evaluation system.
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http://dx.doi.org/10.47176/mjiri.36.55 | DOI Listing |
Int J Biol Macromol
January 2025
Wuhan Third hospital, Tongren Hospital of Wuhan University, 241 Pengliuyang Road, Wuhan 430060, China. Electronic address:
Parkinson's disease (PD), a neurodegenerative disorder without cure, is characterized by the pathological aggregation of α-synuclein (α-Syn) in Lewy bodies. Classic deposition pathway and condensation pathway contribute to α-Syn aggregation, and liquid-liquid phase separation is the driving force for condensate formation, which subsequently undergo liquid-solid phase separation to form toxic fibrils. Traditional Chinese Medicine (TCM) has a long history in treating neurodegenerative disease, herein; we identified chemicals from herbs that inhibit α-Syn aggregation.
View Article and Find Full Text PDFAdv Clin Exp Med
January 2025
Institute of Human Anatomy, Department of Neurosciences, University of Padova, Italy.
The concept of "gender" refers to the socially constructed characteristics that define feminine or masculine behavior, which are constantly changing and can influence access to healthcare and patterns of help-seeking. These factors significantly impact forensic toxicology, a key area within the medicolegal landscape, forcing the adoption of a gender-sensitive approach to better understand the differing impacts of substances on men and women. Research indicates significant disparities in drug use between genders; men are more likely to abuse alcohol and illicit drugs, while women tend to use prescription medications.
View Article and Find Full Text PDFFront Parasitol
December 2023
Population Health and Immunity Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Reticulocyte Binding Protein Homologue (RH5), a leading malaria vaccine candidate, is essential for erythrocyte invasion by the parasite, interacting with the human host receptor, basigin. RH5 has a small number of polymorphisms relative to other blood-stage antigens, and studies have shown that vaccine-induced antibodies raised against RH5 are strain-transcending, however most studies investigating RH5 diversity have been done in Africa. Understanding the genetic diversity and evolution of malaria antigens in other regions is important for their validation as vaccine candidates.
View Article and Find Full Text PDFAcc Chem Res
January 2025
Mineralogical Society of Antwerp, Boterlaarbaan 225, 2100 Deurne, Belgium.
ConspectusWhile photochromic natural sodalites, an aluminosilicate mineral, were originally considered as curiosities, articles published in the past ten years have radically changed this perspective. It has been proven that their artificial synthesis was easy and allowed compositional tuning. Combined with simulations, it has been shown that a wide range of photochromic properties were achievable for synthetic sodalites (color, activation energy, reversibility, etc.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
State Key Laboratory of Nuclear Resources and Environment, East China University of Technology, Nanchang 330013, People's Republic of China.
Visible-light-driven photocatalytic uranium extraction based covalent organic frameworks (COFs) are green and sustainable, but their performance is severely restricted by a strong exciton effect. Herein, inspired by the physiology of cardiac pacing, a novel fluorine-based COF (PyF-DaS-COF) with a biomimetic electronic pump has been fabricated and used for the photocatalytic extraction of uranium. Both experimental and theoretical calculations confirm that strongly electronegative fluorine plays a crucial role in exciton dissociation and charge transfer.
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