Vitreous substitutes are traditionally used to stabilize the retina after vitrectomy. In recent years, various approaches have been developed for using the vitreous substitute not only as a tamponade but also as a drug release system to tackle ocular diseases. This review provides an overview of the requirements for vitreous substitutes and discusses the current clinically applied as well as novel polymer-based vitreous substitutes as drug delivery systems, including their release mechanisms, efficiencies, challenges, and future perspectives.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508686 | PMC |
| http://dx.doi.org/10.1167/tvst.11.9.14 | DOI Listing |
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