This paper introduces a flexible and adaptive nonparametric method for estimating the association between multiple covariates and power spectra of multiple time series. The proposed approach uses a Bayesian sum of trees model to capture complex dependencies and interactions between covariates and the power spectrum, which are often observed in studies of biomedical time series. Local power spectra corresponding to terminal nodes within trees are estimated nonparametrically using Bayesian penalized linear splines. The trees are considered to be random and fit using a Bayesian backfitting Markov chain Monte Carlo (MCMC) algorithm that sequentially considers tree modifications via reversible-jump MCMC techniques. For high-dimensional covariates, a sparsity-inducing Dirichlet hyperprior on tree splitting proportions is considered, which provides sparse estimation of covariate effects and efficient variable selection. By averaging over the posterior distribution of trees, the proposed method can recover both smooth and abrupt changes in the power spectrum across multiple covariates. Empirical performance is evaluated via simulations to demonstrate the proposed method's ability to accurately recover complex relationships and interactions. The proposed methodology is used to study gait maturation in young children by evaluating age-related changes in power spectra of stride interval time series in the presence of other covariates.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024644 | PMC |
http://dx.doi.org/10.1111/biom.13763 | DOI Listing |
Molecules
January 2025
School of Metallurgical and Chemical Engineering, Jiangxi University of Science and Technology, Ganzhou 341000, China.
Isoindigo (IID)-based non-fullerene acceptors, known for their broad absorption spectra and high charge carrier mobilities, play a crucial role in organic photovoltaics. In this study, two A-DA'D-A type unfused ring acceptors (URAs), IDC8CP-IC and IDC6CP-IC, were designed and synthesized using cyclopentadithiophene (CPDT) and IID core units, each functionalized with different alkyl chains (2-hexyldecyl and 2-octyldodecyl), through an atom- and step-efficient direct C-H arylation (DACH) method. Both URAs, despite the absence of non-covalent conformation locking between CPDT and IID, demonstrated favorable molecular planarity, broad absorption ranges, low band gaps, and high molar absorption coefficients.
View Article and Find Full Text PDFBiosensors (Basel)
January 2025
Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.
Hyperspectral imaging (HSI) technology, which offers both spatial and spectral information, holds significant potential for enhancing diagnostic performance during endoscopy and other medical procedures. However, quantitative evaluation of HSI cameras is challenging due to various influencing factors (e.g.
View Article and Find Full Text PDFGels
January 2025
Fisheries Department, Faculty of Marine Sciences, Chabahar Maritime University, Chabahar 9971778631, Iran.
The properties of biopolymer films prepared using Southern meagre fish () skin gelatin blends, both with and without clove bud extract (CE) at concentrations of 0.3% and 0.7%, were investigated.
View Article and Find Full Text PDFLangmuir
January 2025
Surface Science Laboratory, Graduate School of Engineering, Toyota Technological Institute, 2-12-1, Hisakata, Tempaku, Nagoya, Aichi 468-8511, Japan.
Hydrogen-substituted graphdiyne (HsGDY) is a two-dimensional material with an sp-sp carbon skeleton featuring a band gap and a porous structure that enhances ion diffusion. In previous reports, HsGDY growth was limited to metal substrates such as Cu, which then required transfer. Here, we developed a sandwich method that allows HsGDY to be grown directly on the target substrate.
View Article and Find Full Text PDFSTAR Protoc
January 2025
Key Laboratory for Protein Sciences of Ministry of Education, School of Life Sciences, Tsinghua University, Beijing 100084, China; State Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Joint Center for Life Sciences, Beijing 100084, China; Beijing Frontier Research Center for Biological Structure, Beijing 100084, China; School of Life Sciences, Tsinghua University, Beijing 100084, China. Electronic address:
Contrast transfer function (CTF) estimation is essential to the data processing workflow of cryo-electron tomography (cryoET). Here, we present a protocol for CTF estimation of the cryoET tilt series with CTFMeasure. CTFMeasure can estimate the CTF parameters together with the absolute tilt angle offset of the sample.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!